SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02200

Signal sequence   MKLQLMICLVLLPCFFC

Length  17

Organism  Eratigena agrestis (Hobo spider) (Tegenaria agrestis)

UniProt ID  O46166,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02200.cif

Structure  SPKB02200.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2015.68054

Aliphatic index  154.7058824

Isoelectric point  8.045790785

Charge (pH=7)   0.811765118

Topological polar surface area  589.24

Aromaticity  0.117647059

Average rotatable bonds  3.823529412

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  25

X logP energy  1.7694

Hydropathy 



Literature Information


Title  Novel insecticidal peptides from Tegenaria agrestis spider venom may have a direct effect on the insect central nervous system.

DOI  10.1002/(SICI)1520-6327(1998)38:1<19::AID-ARCH3>3.0.CO;2-Q,

Publication Year  1998

PubMed ID  9589602,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.