SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02199

Signal sequence   MALLFSLILAICTRPGFLA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  O43866,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02199.cif

Structure  SPKB02199.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2050.59144

Aliphatic index  159.4736842

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  680.69

Aromaticity  0.105263158

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -1.55063

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.