SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02198

Signal sequence   MDLRQFLMCLSLCTAFALS

Length  19

Organism  Homo sapiens (Human)

UniProt ID  O43852,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02198.cif

Structure  SPKB02198.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2163.65414

Aliphatic index  113.1578947

Isoelectric point  6.064584924

Charge (pH=7)   -0.12552196

Topological polar surface area  790.1

Aromaticity  0.105263158

Average rotatable bonds  3.736842105

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  30

X logP energy  -5.38493

Hydropathy 



Literature Information


Title  Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

DOI  10.1038/nbt810,

Publication Year  2003

PubMed ID  12665801,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.