SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02190

Signal sequence   MVLHSHQLTYAGIAFALCLHHLISA

Length  25

Organism  Gallus gallus (Chicken)

UniProt ID  O42414,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02190.cif

Structure  SPKB02190.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2747.27134

Aliphatic index  136.8

Isoelectric point  7.68526858

Charge (pH=7)   0.298795533

Topological polar surface area  1000.45

Aromaticity  0.08

Average rotatable bonds  3.44

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -5.9088

Hydropathy 



Literature Information


Title  Structure of the axonal surface recognition molecule neurofascin and its relationship to a neural subgroup of the immunoglobulin superfamily.

DOI  10.1083/jcb.118.1.149,

Publication Year  1992

PubMed ID  1377696,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.