SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02189

Signal sequence   MAKLILVTGLAILLNVQLGSS

Length  21

Organism  Mus musculus (Mouse)

UniProt ID  O35744,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8P8R,

Predicted Structure ID  SPKB02189.cif

Structure  SPKB02189.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2154.67974

Aliphatic index  185.7142857

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  818.21

Aromaticity  0

Average rotatable bonds  3.523809524

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -5.5339

Hydropathy 



Literature Information


Title  Identification of a novel eosinophil chemotactic cytokine (ECF-L) as a chitinase family protein.

DOI  10.1074/jbc.275.2.1279,

Publication Year  2000

PubMed ID  10625674,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.