General Information
SPKB ID SPKB02187
Signal sequence MQRAMLLGLLGAAALAAVIS
Length 20
Organism Rattus norvegicus (Rat)
UniProt ID O35314,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02187.cif
Physicochemical Information
Molecular weight 1970.46244
Aliphatic index 161.5
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 741.44
Aromaticity 0
Average rotatable bonds 3.3
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 26
X logP energy -5.04843
Hydropathy
Literature Information
Title The primary structure of human secretogranin I (chromogranin B): comparison with chromogranin A reveals homologous terminal domains and a large intervening variable region.
DOI 10.1002/j.1460-2075.1987.tb02355.x,
Publication Year 1987
PubMed ID 3608978,
Patent ID NA,