SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02186

Signal sequence   MTLLLLGAVLLVAQPQLVHS

Length  20

Organism  Mus musculus (Mouse)

UniProt ID  O35310,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02186.cif

Structure  SPKB02186.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2116.63344

Aliphatic index  190

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  762.75

Aromaticity  0

Average rotatable bonds  3.4

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -3.2994

Hydropathy 



Literature Information


Title  Molecular cloning and expression of mouse and human cDNAs encoding heparan sulfate D-glucosaminyl 3-O-sulfotransferase.

DOI  10.1074/jbc.272.44.28008,

Publication Year  1997

PubMed ID  9346953,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.