SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02183

Signal sequence   MKKLTAAAIATMGFATFTMAHQADA

Length  25

Organism  Staphylococcus aureus (strain NCTC 8325 / PS 47)

UniProt ID  O33599,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02183.cif

Structure  SPKB02183.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2599.07634

Aliphatic index  63.2

Isoelectric point  9.539371756

Charge (pH=7)   1.088749807

Topological polar surface area  1003.75

Aromaticity  0.08

Average rotatable bonds  3.4

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  38

X logP energy  -9.8518

Hydropathy 



Literature Information


Title  Molecular cloning, sequencing, and expression of lytM, a unique autolytic gene of Staphylococcus aureus.

DOI  10.1128/jb.179.11.3625-3631.1997,

Publication Year  1997

PubMed ID  9171409,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.