SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02181

Signal sequence   MRSEMLTALLTLAVLLQVAGS

Length  21

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  O18998,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02181.cif

Structure  SPKB02181.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2217.71064

Aliphatic index  153.3333333

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  868.53

Aromaticity  0

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -6.98003

Hydropathy 



Literature Information


Title  Rabbit DNase I: purification from urine, immunological and proteochemical characterization, nucleotide sequence, expression in tissues, relationships with other mammalian DNases I and phylogenetic analysis.

DOI  10.1042/bj3250465,

Publication Year  1997

PubMed ID  9230129,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.