SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02179

Signal sequence   MKVSEAALSLLVLILIITSASRS

Length  23

Organism  Homo sapiens (Human)

UniProt ID  O15467,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02179.cif

Structure  SPKB02179.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2415.95784

Aliphatic index  173.9130435

Isoelectric point  9.695027686

Charge (pH=7)   0.999461077

Topological polar surface area  950.12

Aromaticity  0

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -7.84313

Hydropathy 



Literature Information


Title  Characterization of a novel CC chemokine, HCC-4, whose expression is increased by interleukin-10.

DOI  NA,

Publication Year  1998

PubMed ID  9596672,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.