General Information
SPKB ID SPKB02178
Signal sequence MRQTLPCIYFWGGLLPFGMLCAS
Length 23
Organism Homo sapiens (Human)
UniProt ID O15455,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7C76,
Predicted Structure ID SPKB02178.cif
Physicochemical Information
Molecular weight 2605.18684
Aliphatic index 89.13043478
Isoelectric point 8.222829177
Charge (pH=7) 0.873181142
Topological polar surface area 867.41
Aromaticity 0.173913043
Average rotatable bonds 3.391304348
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 33
X logP energy -3.35373
Hydropathy
Literature Information
Title Signal peptide prediction based on analysis of experimentally verified cleavage sites.
DOI 10.1110/ps.04682504,
Publication Year 2004
PubMed ID 15340161,
Patent ID NA,