Peptide-Information

General Information

SPKB ID SPKB02174

Signal sequence MERGLPLLCAVLALVLAPAGA

Length 21

Organism Homo sapiens (Human)

UniProt ID O14786,

Motif 1..21

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB02174.cif

Structure SPKB02174.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2078.60244

Aliphatic index 162.8571429

Isoelectric point 6.232433001

Charge (pH=7) -0.062218605

Topological polar surface area 726.94

Aromaticity 0

Average rotatable bonds 3.047619048

Number of hydrogen bond donors 25

Number of hydrogen bond acceptors 26

X logP energy -3.13143

Hydropathy

Literature Information

Title Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity.

Publication Year 2000

PubMed ID 10688880,

Patent ID NA,