General Information
SPKB ID SPKB02172
Signal sequence MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESAL
Length 55
Organism Homo sapiens (Human)
UniProt ID O14763,
Motif 1..55
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02172.cif
Physicochemical Information
Molecular weight 5665.61264
Aliphatic index 92.36363636
Isoelectric point 12.38783597
Charge (pH=7) 6.093605512
Topological polar surface area 2418.09
Aromaticity 0
Average rotatable bonds 3.327272727
Number of hydrogen bond donors 84
Number of hydrogen bond acceptors 77
X logP energy -28.00701
Hydropathy
Literature Information
Title TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.
Publication Year 1997
PubMed ID 9311998,
Patent ID NA,