SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02171

Signal sequence   MSVKGMAIALAVILCATVVQG

Length  21

Organism  Homo sapiens (Human)

UniProt ID  O14625,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8HNK,

Predicted Structure ID  SPKB02171.cif

Structure  SPKB02171.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2075.61434

Aliphatic index  148.5714286

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  754.89

Aromaticity  0

Average rotatable bonds  3.285714286

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  -5.5513

Hydropathy 



Literature Information


Title  Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3).

DOI  10.1046/j.1523-1747.1999.00581.x,

Publication Year  1999

PubMed ID  10233762,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.