SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02168

Signal sequence   MLPRITITIMSWMLLSCLMLLSQVQG

Length  26

Organism  Mus musculus (Mouse)

UniProt ID  O09049,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02168.cif

Structure  SPKB02168.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2979.76714

Aliphatic index  146.1538462

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  1047.05

Aromaticity  0.038461538

Average rotatable bonds  3.807692308

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  40

X logP energy  -5.07423

Hydropathy 



Literature Information


Title  Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment.

DOI  10.1074/jbc.M808077200,

Publication Year  2009

PubMed ID  19095652,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.