SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02167

Signal sequence   MLLLLLLLLPLCWA

Length  14

Organism  Mus musculus (Mouse)

UniProt ID  O08795,

Motif  1..14



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02167.cif

Structure  SPKB02167.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1625.18994

Aliphatic index  257.8571429

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  448.62

Aromaticity  0.071428571

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  16

Number of hydrogen bond acceptors  17

X logP energy  5.0486

Hydropathy 



Literature Information


Title  Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II.

DOI  10.1074/jbc.272.20.13117,

Publication Year  1997

PubMed ID  9148925,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.