SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02165

Signal sequence   MLKKIKISLILALGLTSLQAFG

Length  22

Organism  Elizabethkingia meningoseptica (Chryseobacterium meningosepticum)

UniProt ID  O08498,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02165.cif

Structure  SPKB02165.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2358.99494

Aliphatic index  168.6363636

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  856.26

Aromaticity  0.045454545

Average rotatable bonds  3.818181818

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -3.6897

Hydropathy 



Literature Information


Title  Characterization and sequence of the Chryseobacterium (Flavobacterium) meningosepticum carbapenemase: a new molecular class B beta-lactamase showing a broad substrate profile.

DOI  10.1042/bj3320145,

Publication Year  1998

PubMed ID  9576862,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.