SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02159

Signal sequence   MMAFCALRKALPCRPENPFSSRCFVEILWVSLALVFLLPMPSDA

Length  44

Organism  Sus scrofa (Pig)

UniProt ID  O02839,

Motif  1..44



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02159.cif

Structure  SPKB02159.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4972.05234

Aliphatic index  102.0454545

Isoelectric point  8.045902316

Charge (pH=7)   0.815751914

Topological polar surface area  1734.09

Aromaticity  0.113636364

Average rotatable bonds  3.477272727

Number of hydrogen bond donors  62

Number of hydrogen bond acceptors  63

X logP energy  -9.07679

Hydropathy 



Literature Information


Title  Purification and characterization of the pig analogue of human membrane cofactor protein (CD46/MCP).

DOI  NA,

Publication Year  1997

PubMed ID  9029106,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.