General Information
SPKB ID SPKB02157
Signal sequence MRLHRLRARLSAVACGLLLLLVRGQG
Length 26
Organism Homo sapiens (Human)
UniProt ID O00748,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02157.cif
Physicochemical Information
Molecular weight 2873.56664
Aliphatic index 153.8461538
Isoelectric point 12.67614599
Charge (pH=7) 5.026902118
Topological polar surface area 1192.32
Aromaticity 0
Average rotatable bonds 3.807692308
Number of hydrogen bond donors 46
Number of hydrogen bond acceptors 37
X logP energy -9.62415
Hydropathy 
Literature Information
Title Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin.
Publication Year 1997
PubMed ID 9169443,
Patent ID NA,
