General Information
SPKB ID SPKB02156
Signal sequence MDRLQTALLVVLVLLAVALQATEA
Length 24
Organism Homo sapiens (Human)
UniProt ID O00626,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02156.cif
Physicochemical Information
Molecular weight 2552.11124
Aliphatic index 182.9166667
Isoelectric point 4.184407676
Charge (pH=7) -0.999797405
Topological polar surface area 995.76
Aromaticity 0
Average rotatable bonds 3.541666667
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 33
X logP energy -5.75663
Hydropathy
Literature Information
Title Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells.
Publication Year 1997
PubMed ID 9151897,
Patent ID NA,