SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02155

Signal sequence   MELSGATMARGLAVLLVLFLHIKNLPAQA

Length  29

Organism  Homo sapiens (Human)

UniProt ID  O00602,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02155.cif

Structure  SPKB02155.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3078.76794

Aliphatic index  144.8275862

Isoelectric point  9.697026921

Charge (pH=7)   1.090370168

Topological polar surface area  1149.87

Aromaticity  0.034482759

Average rotatable bonds  3.517241379

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  40

X logP energy  -6.99223

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.