SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02151

Signal sequence   MMSASRLAGTLIPAMAFLSCVRP

Length  23

Organism  Homo sapiens (Human)

UniProt ID  O00206,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02151.cif

Structure  SPKB02151.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2423.99384

Aliphatic index  97.82608696

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  890.66

Aromaticity  0.043478261

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -8.05626

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.