General Information
SPKB ID SPKB02147
Signal sequence MKVLRCLVCSFYIIVSLITTMTIG
Length 24
Organism Rhipicephalus appendiculatus (Brown ear tick)
UniProt ID M1MR49,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02147.cif
Physicochemical Information
Molecular weight 2705.42944
Aliphatic index 150
Isoelectric point 8.798094803
Charge (pH=7) 1.872886108
Topological polar surface area 941.92
Aromaticity 0.083333333
Average rotatable bonds 3.708333333
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 37
X logP energy -4.45313
Hydropathy
Literature Information
Title Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses.
DOI 10.1371/journal.ppat.1003450,
Publication Year 2013
PubMed ID 23825947,
Patent ID NA,