SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02143

Signal sequence   MNVFFMFSLLFLAALGSC

Length  18

Organism  Lachesis muta (South American bushmaster)

UniProt ID  J7H670,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02143.cif

Structure  SPKB02143.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2011.48554

Aliphatic index  113.8888889

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  641.57

Aromaticity  0.222222222

Average rotatable bonds  3.5

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  -1.5817

Hydropathy 



Literature Information


Title  Isolation and biochemical, functional and structural characterization of a novel L-amino acid oxidase from Lachesis muta snake venom.

DOI  10.1016/j.toxicon.2012.08.008,

Publication Year  2012

PubMed ID  22963728,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.