SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02142

Signal sequence   MRFLALTSLLCILLLCLSFFSAEG

Length  24

Organism  Sus scrofa (Pig)

UniProt ID  I3LGZ3,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02142.cif

Structure  SPKB02142.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2662.30204

Aliphatic index  154.5833333

Isoelectric point  6.135737489

Charge (pH=7)   -0.124193321

Topological polar surface area  912.74

Aromaticity  0.125

Average rotatable bonds  3.625

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -3.53863

Hydropathy 



Literature Information


Title  A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia.

DOI  10.1126/scisignal.aal0180,

Publication Year  2017

PubMed ID  28900043,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.