General Information
SPKB ID SPKB02141
Signal sequence MSSGGLLLLLGLLTLWAELTPVSS
Length 24
Organism Macrovipera lebetina transmediterranea (Blunt-nosed viper) (Vipera lebetina transmediterranea)
UniProt ID I2G9B4,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02141.cif
Physicochemical Information
Molecular weight 2471.97794
Aliphatic index 162.5
Isoelectric point 3.849983241
Charge (pH=7) -1.000240578
Topological polar surface area 898.3
Aromaticity 0.041666667
Average rotatable bonds 3.291666667
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 33
X logP energy -5.8874
Hydropathy 
Literature Information
Title PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells.
DOI 10.1016/j.matbio.2012.11.015,
Publication Year 2013
PubMed ID 23262217,
Patent ID NA,
