SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02136

Signal sequence   MDKMNPAHLLVLAAVCVSLLGASSIPPQAL

Length  30

Organism  Micrurus tener tener (Texas coral snake)

UniProt ID  G9I930,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02136.cif

Structure  SPKB02136.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3060.72174

Aliphatic index  136.6666667

Isoelectric point  7.359000943

Charge (pH=7)   0.027070125

Topological polar surface area  1119.72

Aromaticity  0

Average rotatable bonds  3.2

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  42

X logP energy  -8.879

Hydropathy 



Literature Information


Title  A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain.

DOI  10.1038/nature10607,

Publication Year  2011

PubMed ID  22094702,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.