SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02134

Signal sequence   MSRFLIYFLPFFIYSGNVLS

Length  20

Organism  Caenorhabditis elegans

UniProt ID  G5ED35,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02134.cif

Structure  SPKB02134.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2414.89034

Aliphatic index  112

Isoelectric point  9.17162813

Charge (pH=7)   0.99628016

Topological polar surface area  813.57

Aromaticity  0.3

Average rotatable bonds  3.65

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -1.63033

Hydropathy 



Literature Information


Title  Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor.

DOI  10.1038/ncb2068,

Publication Year  2010

PubMed ID  20526330,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.