General Information
SPKB ID SPKB02125
Signal sequence MAGKLGVLLLALVLSLAQPASA
Length 22
Organism Bos taurus (Bovine)
UniProt ID F1N5C8,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02125.cif
Physicochemical Information
Molecular weight 2136.66454
Aliphatic index 173.1818182
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 775.2
Aromaticity 0
Average rotatable bonds 3.181818182
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 28
X logP energy -4.7855
Hydropathy
Literature Information
Title Bovine brain myelin glycerophosphocholine choline phosphodiesterase is an alkaline lysosphingomyelinase of the eNPP-family, regulated by lysosomal sorting.
DOI 10.1007/s11064-012-0921-z,
Publication Year 2013
PubMed ID 23161088,
Patent ID NA,