SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02119

Signal sequence   MTDWSRRRFLQTGAALGIAGTLPQTTTEVSA

Length  31

Organism  Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)

UniProt ID  D4GPK6,

Motif  1..31



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02119.cif

Structure  SPKB02119.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3336.77044

Aliphatic index  72.58064516

Isoelectric point  10.30863985

Charge (pH=7)   1.000195972

Topological polar surface area  1451.64

Aromaticity  0.064516129

Average rotatable bonds  3.451612903

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  48

X logP energy  -18.08779

Hydropathy 



Literature Information


Title  LccA, an archaeal laccase secreted as a highly stable glycoprotein into the extracellular medium by Haloferax volcanii.

DOI  10.1128/AEM.01757-09,

Publication Year  2010

PubMed ID  19966030,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.