SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02113

Signal sequence   MKRQLYLYVIFVVVELMVFTTKGYS

Length  25

Organism  Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)

UniProt ID  C6XZB6,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02113.cif

Structure  SPKB02113.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3028.70444

Aliphatic index  120.4

Isoelectric point  9.736901871

Charge (pH=7)   1.9966148

Topological polar surface area  1077.43

Aromaticity  0.2

Average rotatable bonds  3.96

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  39

X logP energy  -2.62873

Hydropathy 



Literature Information


Title  Isolation and expression in Escherichia coli of hepB and hepC, genes coding for the glycosaminoglycan-degrading enzymes heparinase II and heparinase III, respectively, from Flavobacterium heparinum.

DOI  10.1128/aem.62.8.2723-2734.1996,

Publication Year  1996

PubMed ID  8702264,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.