General Information
SPKB ID SPKB02113
Signal sequence MKRQLYLYVIFVVVELMVFTTKGYS
Length 25
Organism Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)
UniProt ID C6XZB6,
Motif 1..25
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02113.cif
Physicochemical Information
Molecular weight 3028.70444
Aliphatic index 120.4
Isoelectric point 9.736901871
Charge (pH=7) 1.9966148
Topological polar surface area 1077.43
Aromaticity 0.2
Average rotatable bonds 3.96
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 39
X logP energy -2.62873
Hydropathy
Literature Information
Title Isolation and expression in Escherichia coli of hepB and hepC, genes coding for the glycosaminoglycan-degrading enzymes heparinase II and heparinase III, respectively, from Flavobacterium heparinum.
DOI 10.1128/aem.62.8.2723-2734.1996,
Publication Year 1996
PubMed ID 8702264,
Patent ID NA,