SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02110

Signal sequence   MAFLVFAFLTLMAVETYG

Length  18

Organism  Pithecopus azureus (Orange-legged monkey tree frog) (Phyllomedusa azurea)

UniProt ID  C0HLL2,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02110.cif

Structure  SPKB02110.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2024.46364

Aliphatic index  113.8888889

Isoelectric point  3.849982713

Charge (pH=7)   -1.001090992

Topological polar surface area  656.01

Aromaticity  0.222222222

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  -0.4097

Hydropathy 



Literature Information


Title  Identification and characterization of phospholipases A(2) from the skin secretion of Pithecopus azureus anuran.

DOI  10.1016/j.toxicon.2019.06.002,

Publication Year  2019

PubMed ID  31173792,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.