SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02109

Signal sequence   MRVVVVVTGLVVVVVATA

Length  18

Organism  Conus purpurascens (Purple cone)

UniProt ID  C0HKM3,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02109.cif

Structure  SPKB02109.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1811.30044

Aliphatic index  193.8888889

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  660.38

Aromaticity  0

Average rotatable bonds  3.111111111

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  -3.30483

Hydropathy 



Literature Information


Title  Isolation and characterization of Conohyal-P1, a hyaluronidase from the injected venom of Conus purpurascens.

DOI  10.1016/j.jprot.2017.05.002,

Publication Year  2017

PubMed ID  28479398,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.