SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02108

Signal sequence   MGISKKSQLVPLLAFITMFLMVVSRVSS

Length  28

Organism  Dioclea lasiophylla

UniProt ID  C0HK27,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02108.cif

Structure  SPKB02108.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3083.84294

Aliphatic index  128.5714286

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1118.64

Aromaticity  0.071428571

Average rotatable bonds  3.714285714

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  42

X logP energy  -7.58023

Hydropathy 



Literature Information


Title  Molecular modeling, docking and dynamics simulations of the Dioclea lasiophylla Mart. Ex Benth seed lectin: An edematogenic and hypernociceptive protein.

DOI  10.1016/j.biochi.2017.02.002,

Publication Year  2017

PubMed ID  28196677,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.