General Information
SPKB ID SPKB02107
Signal sequence MKRFLLFISILMMIGTIVVG
Length 20
Organism Tityus fasciolatus (Central Brazilian scorpion)
UniProt ID C0HJM9,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02107.cif
Physicochemical Information
Molecular weight 2282.97594
Aliphatic index 165.5
Isoelectric point 11.65177567
Charge (pH=7) 1.997685954
Topological polar surface area 744.6
Aromaticity 0.1
Average rotatable bonds 3.9
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 28
X logP energy 0.01707
Hydropathy
Literature Information
Title The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening.
DOI 10.1371/journal.pone.0128578,
Publication Year 2015
PubMed ID 26083731,
Patent ID NA,