General Information
SPKB ID SPKB02103
Signal sequence MASFKSFLLLALLAIVSEA
Length 19
Organism Xenopus laevis (African clawed frog)
UniProt ID B7ZS96,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02103.cif
Physicochemical Information
Molecular weight 2024.48944
Aliphatic index 159.4736842
Isoelectric point 6.408795646
Charge (pH=7) -0.000535612
Topological polar surface area 711.13
Aromaticity 0.105263158
Average rotatable bonds 3.526315789
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 26
X logP energy -2.6539
Hydropathy
Literature Information
Title Evolution of structure, ontogeny of gene expression, and function of Xenopus laevis transthyretin.
DOI 10.1152/ajpregu.2000.279.6.R2026,
Publication Year 2000
PubMed ID 11080066,
Patent ID NA,