SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02103

Signal sequence   MASFKSFLLLALLAIVSEA

Length  19

Organism  Xenopus laevis (African clawed frog)

UniProt ID  B7ZS96,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02103.cif

Structure  SPKB02103.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2024.48944

Aliphatic index  159.4736842

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  711.13

Aromaticity  0.105263158

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -2.6539

Hydropathy 



Literature Information


Title  Evolution of structure, ontogeny of gene expression, and function of Xenopus laevis transthyretin.

DOI  10.1152/ajpregu.2000.279.6.R2026,

Publication Year  2000

PubMed ID  11080066,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.