Peptide-Information

General Information

SPKB ID SPKB02096

Signal sequence MKGTFLICLILIAGFSFKSTQA

Length 22

Organism Radianthus crispa (Leathery sea anemone) (Heteractis crispa)

UniProt ID B2G331,

Motif 1..22

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB02096.cif

Structure SPKB02096.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2389.93974

Aliphatic index 115.4545455

Isoelectric point 9.676237541

Charge (pH=7) 1.935419516

Topological polar surface area 850.47

Aromaticity 0.136363636

Average rotatable bonds 3.636363636

Number of hydrogen bond donors 31

Number of hydrogen bond acceptors 32

X logP energy -5.161

Hydropathy

Literature Information

Title Analgesic compound from sea anemone Heteractis crispa is the first polypeptide inhibitor of vanilloid receptor 1 (TRPV1).

Publication Year 2008

PubMed ID 18579526,

Patent ID NA,