SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02083

Signal sequence   MGIHQCTAVVLLLLCASLSTYG

Length  22

Organism  Danio rerio (Zebrafish) (Brachydanio rerio)

UniProt ID  A5HAK0,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02083.cif

Structure  SPKB02083.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2293.78284

Aliphatic index  141.8181818

Isoelectric point  7.250885854

Charge (pH=7)   -0.035906456

Topological polar surface area  847.34

Aromaticity  0.045454545

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -6.9912

Hydropathy 



Literature Information


Title  Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications.

DOI  10.1016/j.jmb.2008.04.070,

Publication Year  2008

PubMed ID  18508078,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.