SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02082

Signal sequence   MRTLWIVAVCLIGVEG

Length  16

Organism  Vipera nikolskii (Nikolsky's adder) (Vipera berus nikolskii)

UniProt ID  A4VBF0,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02082.cif

Structure  SPKB02082.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1760.18594

Aliphatic index  158.125

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.5

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  22

X logP energy  -1.97883

Hydropathy 



Literature Information


Title  Heterodimeric neurotoxic phospholipases A2--the first proteins from venom of recently established species Vipera nikolskii: implication of venom composition in viper systematics.

DOI  10.1016/j.toxicon.2007.11.001,

Publication Year  2008

PubMed ID  18083205,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.