SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02077

Signal sequence   MRLILLSGLLLLGTFLANG

Length  19

Organism  Metlapilcoatlus nummifer (Mexican jumping pitviper) (Atropoides nummifer)

UniProt ID  A1XRN2,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02077.cif

Structure  SPKB02077.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2015.52814

Aliphatic index  190

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  732.57

Aromaticity  0.052631579

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  25

X logP energy  -3.03873

Hydropathy 



Literature Information


Title  Isolation, characterization and molecular cloning of AnMIP, a new alpha-type phospholipase A2 myotoxin inhibitor from the plasma of the snake Atropoides nummifer (Viperidae: Crotalinae).

DOI  10.1016/j.cbpb.2006.09.003,

Publication Year  2007

PubMed ID  17071122,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.