SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02073

Signal sequence   MPEQDLASGFLLRFQNARPVCLSVGSFVSFRTVQPRKMRDRGWRCVWHRMAGVGALFGIFGVLCTVEAGA

Length  70

Organism  Toxoplasma gondii

UniProt ID  A0A7J6K7Y0,

Motif  1..70



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02073.cif

Structure  SPKB02073.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7788.15244

Aliphatic index  80.71428571

Isoelectric point  11.13109055

Charge (pH=7)   4.907090932

Topological polar surface area  3069.27

Aromaticity  0.114285714

Average rotatable bonds  3.585714286

Number of hydrogen bond donors  113

Number of hydrogen bond acceptors  101

X logP energy  -27.65504

Hydropathy 



Literature Information


Title  Aspartyl Protease 5 Matures Dense Granule Proteins That Reside at the Host-Parasite Interface in Toxoplasma gondii.

DOI  10.1128/mBio.01796-18,

Publication Year  2018

PubMed ID  30377279,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.