SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02072

Signal sequence   MMFPAVAAPPRRLPGERLQRSQNPVETSWLSFRILATRGPCVTSTFLFLTVAFLGLSWVSVAVA

Length  64

Organism  Toxoplasma gondii

UniProt ID  A0A7J6K7I9,

Motif  1..64



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02072.cif

Structure  SPKB02072.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7049.33484

Aliphatic index  97.5

Isoelectric point  12.19911708

Charge (pH=7)   3.939539961

Topological polar surface area  2673.26

Aromaticity  0.109375

Average rotatable bonds  3.375

Number of hydrogen bond donors  96

Number of hydrogen bond acceptors  90

X logP energy  -22.31078

Hydropathy 



Literature Information


Title  Aspartyl Protease 5 Matures Dense Granule Proteins That Reside at the Host-Parasite Interface in Toxoplasma gondii.

DOI  10.1128/mBio.01796-18,

Publication Year  2018

PubMed ID  30377279,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.