SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02069

Signal sequence   MRTLWIMAVLLLGVEG

Length  16

Organism  Agkistrodon piscivorus leucostoma (Western cottonmouth) (Acontias leucostoma)

UniProt ID  A0A411EZW9,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02069.cif

Structure  SPKB02069.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1802.26654

Aliphatic index  164.375

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.6875

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -0.76543

Hydropathy 



Literature Information


Title  Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A(2,) AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom.

DOI  10.1016/j.toxicon.2017.01.002,

Publication Year  2017

PubMed ID  28063838,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.