SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02067

Signal sequence   MEKKIIFLVFLVALLALPGFIST

Length  23

Organism  Scolopendra mutilans (Chinese red-headed centipede) (Scolopendra subspinipes mutilans)

UniProt ID  A0A2L0ART2,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02067.cif

Structure  SPKB02067.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2564.25124

Aliphatic index  169.5652174

Isoelectric point  9.537300927

Charge (pH=7)   0.999169354

Topological polar surface area  824.53

Aromaticity  0.130434783

Average rotatable bonds  3.652173913

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  0.8992

Hydropathy 



Literature Information


Title  Centipedes subdue giant prey by blocking KCNQ channels.

DOI  10.1073/pnas.1714760115,

Publication Year  2018

PubMed ID  29358396,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.