SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02066

Signal sequence   MAFKPKIPIALLLLTSLLAICAGLALA

Length  27

Organism  Juglans regia (English walnut)

UniProt ID  A0A2I4E5L6,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02066.cif

Structure  SPKB02066.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2766.56624

Aliphatic index  181.1111111

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  894.84

Aromaticity  0.037037037

Average rotatable bonds  3.296296296

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  34

X logP energy  -1.1699

Hydropathy 



Literature Information


Title  Jug r 6 is the allergenic vicilin present in walnut responsible for IgE cross-reactivities to other tree nuts and seeds.

DOI  10.1038/s41598-018-29656-4,

Publication Year  2018

PubMed ID  30054513,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.