SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02063

Signal sequence   MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANA

Length  36

Organism  Staphylococcus aureus (strain Newman)

UniProt ID  A0A0H3K686,

Motif  1..36



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02063.cif

Structure  SPKB02063.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3643.38964

Aliphatic index  121.9444444

Isoelectric point  11.28114271

Charge (pH=7)   4.995950438

Topological polar surface area  1466.8

Aromaticity  0.027777778

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  52

X logP energy  -15.20333

Hydropathy 



Literature Information


Title  Release of protein A from the cell wall of Staphylococcus aureus.

DOI  10.1073/pnas.1317181111,

Publication Year  2014

PubMed ID  24434550,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.