SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02062

Signal sequence   MKLSVSIFVLLAVSAFGGGSA

Length  21

Organism  Mycosarcoma maydis (Corn smut fungus) (Ustilago maydis)

UniProt ID  A0A0D1DWQ2,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02062.cif

Structure  SPKB02062.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2054.47544

Aliphatic index  130

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  752.26

Aromaticity  0.095238095

Average rotatable bonds  3.19047619

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -6.4627

Hydropathy 



Literature Information


Title  A kiwellin disarms the metabolic activity of a secreted fungal virulence factor.

DOI  10.1038/s41586-018-0857-9,

Publication Year  2019

PubMed ID  30651637,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.