General Information
SPKB ID SPKB02061
Signal sequence MEIKYLLTVFLVLLIVSDHCQA
Length 22
Organism Androctonus crassicauda (Arabian fat-tailed scorpion)
UniProt ID A0A0A1I6E7,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02061.cif
Physicochemical Information
Molecular weight 2549.12494
Aliphatic index 168.1818182
Isoelectric point 5.451763262
Charge (pH=7) -0.972005167
Topological polar surface area 907.5
Aromaticity 0.090909091
Average rotatable bonds 3.818181818
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 33
X logP energy -2.1635
Hydropathy
Literature Information
Title Cationicity-enhanced analogues of the antimicrobial peptides, AcrAP1 and AcrAP2, from the venom of the scorpion, Androctonus crassicauda, display potent growth modulation effects on human cancer cell lines.
DOI 10.7150/ijbs.9859,
Publication Year 2014
PubMed ID 25332684,
Patent ID NA,