SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02053

Signal sequence   SPTTSPSTTASLVSTSVTSSVTLTSTDVTTSEDTTGFVLPDSGTSSGTADALEAYSIGITSSSAVVDSKKRDA

Length  73

Organism  Artificial

UniProt ID  NA,

Motif  1..73



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02053.cif

Structure  SPKB02053.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7193.67044

Aliphatic index  68.08219178

Isoelectric point  3.812630859

Charge (pH=7)   -4.997230343

Topological polar surface area  3252.54

Aromaticity  0.02739726

Average rotatable bonds  3.136986301

Number of hydrogen bond donors  119

Number of hydrogen bond acceptors  120

X logP energy  -56.41963

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.