SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02052

Signal sequence   ASSGRSPTITGQVSTLSSTDGTLPTSFTSGSAAGTISSTLPSNVTSTLGTIDLSPNGSADSSSKRST

Length  67

Organism  Artificial

UniProt ID  NA,

Motif  1..67



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02052.cif

Structure  SPKB02052.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6451.88284

Aliphatic index  61.19402985

Isoelectric point  6.522001828

Charge (pH=7)   -0.000977905

Topological polar surface area  2987.11

Aromaticity  0.014925373

Average rotatable bonds  3.074626866

Number of hydrogen bond donors  109

Number of hydrogen bond acceptors  109

X logP energy  -57.25716

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.